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How Treatment May Help

PROMACTA

How Treatment May Help You

If your platelets are still low after other treatments have not worked, PROMACTA could help.

PROMACTA® (eltrombopag) is a prescription medicine used to treat low blood platelet counts in people with chronic ITP when corticosteroids, immunoglobulins, or surgery to remove the spleen have not worked well enough.

 

PROMACTA should be used only in people with chronic ITP whose low blood platelet counts and clinical condition increase their risk for bleeding. PROMACTA is not used to make your platelet count normal.

 

Three separate clinical studies have demonstrated the risks and benefits of taking PROMACTA for chronic ITP.

 

In 2 studies in which adult patients received either PROMACTA or placebo for up to 6 weeks:

 

  • PROMACTA helped increase platelet counts to target levels*
  • With PROMACTA, platelet counts increased as early as 1 to 2 weeks after starting treatment and decreased within 1 to 2 weeks after stopping treatment

 

In a third study, in which adult patients received either PROMACTA or placebo for 6 months:

 

  • Over the course of the 6-month study, 37% to 56% of patients receiving PROMACTA increased and maintained platelet counts within the target range
  • 59% of patients taking PROMACTA were able to stop other medications for chronic ITP, such as corticosteroids or intravenous immunoglobulins (IVIgs)

 

*Target levels defined as platelet counts greater than or equal to 50,000/mcL at the end of 6 weeks.

Target range defined as platelet counts between 50,000/mcL and 400,000/mcL during the 6-month period that patients received PROMACTA or placebo.

 

Need help talking with your health care team about your treatment? Download the PROMACTA Discussion Guide

What to Expect When You’re Starting PROMACTA

Learning how to make a new medicine part of your routine can take time. Each of the patients below had a different concern about starting treatment with PROMACTA. Does anything sound familiar? While everyone is unique, you may find it helpful to learn about other people’s experiences.

 

Select each patient to learn more about his or her experience with taking PROMACTA.

When I first started taking PROMACTA, sometimes I took my medicine with food. But my doctor explained that PROMACTA only works if you take it exactly as prescribed. That means taking PROMACTA on an empty stomach, either 1 hour before eating or 2 hours after eating. It’s also important to take PROMACTA either 2 hours before or 4 hours after eating foods or taking medicines that keep my body from absorbing PROMACTA. These include dairy products, calcium-rich foods, antacids, multivitamins, and other supplements that contain iron, calcium, aluminium, magnesium, selenium, or zinc. Taking PROMACTA exactly as my doctor prescribed is how I do my part to help manage my condition.

I’ll be the first to admit that I’m not the most patient person in the world. So when I started on PROMACTA, I wanted to know immediately if it was working. But because you may not feel any difference, especially in the beginning, it’s hard to know. That’s why I liked having regular blood tests. You have to go every week for a platelet count and every 2 weeks to check your liver function, which was great because I could see the numbers for myself. Now that my PROMACTA dose is set, I only need to get blood tests every month.   

When my doctor first mentioned PROMACTA, I have to admit that I was uncertain about trying another medicine. But he explained that while my current medicine helped prevent existing platelets from being destroyed, PROMACTA actually increases the number of platelets being made. And the fact that PROMACTA is a once-a-day pill means that I can take it at the time that works best for me, wherever I am.

Being diagnosed with chronic ITP
Do you share any of the same thoughts or concerns as Anna, David, or Donna? Click here to read how other people have reacted to being diagnosed with chronic ITP.

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