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How to Take Treatment

PROMACTA

How to Take

3 rules for taking PROMACTA

PROMACTA® (eltrombopag) is a once-daily tablet you can take wherever is convenient for you. However, it is important that you take PROMACTA properly in order for it to work best.

 

Follow these 3 rules to help PROMACTA treat your chronic ITP:

 

Take PROMACTA every day.

To keep things simple, try to take PROMACTA at the same time every day. It might be easiest to take it at bedtime or first thing in the morning. 

 

Do not take PROMACTA with food.

Take PROMACTA on an empty stomach, either 1 hour before or 2 hours after eating.

 

Do not take PROMACTA with calcium-rich products.

Too much calcium (more than 50 mg) stops PROMACTA from working properly.*

 

To get the full benefit of PROMACTA, take your tablet at least 2 hours before or 4 hours after eating dairy products and calcium-fortified juices.

 

 

*Just 1 slice of American cheese has 150 mg of calcium.

 

Click here for some low-calcium recipes to help get you started.

Let’s look at this in practice

One sample schedule would be if you took PROMACTA in the morning, before work. Say work starts at 9 AM. You would:

  • Wake up and take PROMACTA immediately at 7 AM.
  • Wait 1 hour before eating a breakfast with less than 50 mg of calcium.
  • Resume your normal eating schedule from 9 AM onward, 2 hours after you took PROMACTA.

Need more help with the rules regarding PROMACTA and food? Download our meal planner here.

Below are a few other sample schedules.

When taking PROMACTA, timing matters

Click each tab below to see how the time you take your PROMACTA shapes your daily routine.

If you take PROMACTA first thing in the morning, your schedule might look something like this:

 

6 AM   WAKE UP AND TAKE PROMACTA
AM- 7 AM
 

No food

PROMACTA should be taken either 1 hour before or 2 hours after eating

7 AM- 8 AM
 

Modified eating schedule

For 4 hours before taking PROMACTA and 2 hours after taking PROMACTA, avoid dairy products and calcium-rich foods. Examples of calcium-rich foods include:


 Yogurt

Plain, low-fat yogurt has 448 mg of calcium per 8-oz serving

 Bowl of cereal

While 1 cup of plain cornflakes contains only 1 mg of calcium, a cup of milk adds another 293 mg 

 Protein shake

A protein shake contains approximately 334 mg of calcium


Instead, try:

 Fried egg

Contains only 29 mg of calcium

 Blueberries

One cup contains 9 mg of calcium

 Plain bagel

One bagel contains 24 mg of calcium

AM
 

No eating restrictions

2 hours have passed since taking PROMACTA, so there are no restrictions on your food choices

Let’s see how much you know about taking PROMACTA in the morning.

Click the food choice that fits into a low-calcium diet.

Yogurt Yogurt
Fried egg Fried egg
Protein shake Protein shake

Try again. : An 8 oz serving of plain, low-fat yogurt has 448 mg of calcium.

Good job! : With only 29 mg of calcium, a fried egg is a good low-calcium choice.

Try again. : A protein shake contains approximately 334 mg of calcium.

If you take PROMACTA at bedtime, your schedule might look something like this. 

 

PM- 9 PM
 

Modified eating schedule

For 4 hours before taking PROMACTA and 2 hours after taking PROMACTA, avoid dairy products and calcium-rich foods. Examples of calcium-rich foods include:

 

 Spinach 

A bunch of spinach has 337 mg of calcium

 Macaroni and cheese

One cup contains 161 mg of calcium

 Lasagna

A 1-cup serving contains 250 mg of calcium


Instead, try:

 Asparagus

One cup contains only 32 mg of calcium

 Chicken breast

Contains only 14 mg of calcium

 Popcorn

Contains no calcium

9 PM- 11 PM
 

No food

PROMACTA should be taken either 1 hour before or 2 hours after eating.

11 PM   TAKE PROMACTA, GO TO SLEEP

Let’s see how much you know about taking PROMACTA around bedtime.

Click the food choice below that’s low in calcium.

Macaroni and cheese Macaroni and cheese
Chicken breast Chicken breast
Lasagna Lasagna

Try again. : One cup of macaroni and cheese contains 161 mg of calcium, making it a high-calcium food.

Good job! : There are only 14 mg of calcium in a chicken breast, making it a low-calcium choice.

Try again. : With 250 mg of calcium per 1-cup serving, lasagna is a high-calcium food.

If you take PROMACTA in the middle of the night, your schedule might look something like this.

 

10 PM- 12 AM
 

Modified eating schedule

For 4 hours before taking PROMACTA and 2 hours after taking PROMACTA, avoid dairy products and calcium-rich foods. Examples of calcium-rich foods include:


 Almonds

One cup has 385 mg of calcium

 Chocolate ice cream

One cup has 144 mg of calcium

 Pepperoni pizza

A single slice has 201 mg of calcium


Instead, try:

 Grapes

One cup contains only 15 mg of calcium

 Pretzels

A 1.5-oz serving has only 11 mg of calcium

 Chocolate chip cookies

Two cookies have only 6 mg calcium—just be sure to skip the milk!

12 AM- 2 AM
 

No food

PROMACTA should be taken either 1 hour before or 2 hours after eating.

2 AM   WAKE UP AND TAKE PROMACTA
AM
 

No eating restrictions

2 hours have passed since taking PROMACTA, so there are no restrictions on your food choices.

Let's see how much you know about taking PROMACTA during the night.

Which food choice fits into a low-calcium diet?

Cookies Cookies
Pepperoni pizza Pepperoni pizza
Almonds Almonds

Good job! : Two chocolate chip cookies have only 6 mg of calcium.

Try again. : Try again. With 201 mg of calcium per slice, pepperoni pizza is a high-calcium choice

Try again. : A cup of almonds has 385 mg of calcium, making it a high-calcium food.

Unsure whether you’ve reached the calcium limit? The USDA database is a great place to check the calcium content of specific foods.