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Understanding Side Effects


Understanding Side Effects

In adult chronic ITP clinical trials, the most common side effects of PROMACTA were:

  • nausea
  • diarrhea
  • upper respiratory tract infection. Symptoms may include runny nose, stuffy nose, and sneezing
  • vomiting
  • muscle aches
  • urinary tract infection. Symptoms may include frequent or urgent need to urinate, low fever in some people, pain or burning with urination
  • pain or swelling (inflammation) in your throat or mouth (oropharyngeal pain and pharyngitis)
  • abnormal liver function tests
  • back pain
  • “flu”-like symptoms (influenza) including fever, headache, tiredness, cough, sore throat, and body aches
  • skin tingling, itching, or burning
  • rash


It’s important to talk about your treatment experience with your health care team. Want help getting the conversation started? Download the PROMACTA Discussion Guide.


Always keep an eye on how your body reacts to new medication. Contact your doctor if your ITP symptoms don’t seem to be improving, and tell your doctor about any bruising or bleeding that happens while you take, and after you stop taking, PROMACTA® (eltrombopag).


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088.