Frequently Asked Questions


Find help for common questions

Whether you are curious about PROMACTA® (eltrombopag) as a treatment for persistent or chronic immune thrombocytopenia (ITP) or about ITP in general, here is a quick guide with answers to common questions so you can take a more active role in discussions with your doctor.


You can also watch the video below, featuring practicing hematologist Dr Morey A. Blinder, Professor of Medicine, Division of Hematology, at Washington University in St Louis, Missouri. Here, Dr Blinder discusses topics such as: What persistent or chronic ITP is, what PROMACTA is, how PROMACTA works, what dietary considerations are associated with PROMACTA, and how you should take PROMACTA.

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  • PROMACTA is the only oral prescription platelet booster used to treat adults and children 1 year and older with persistent or chronic ITP
  • PROMACTA may be used after an initial ITP treatment, such as a steroid or intravenous immunoglobulin (IVIg), has failed to keep your platelets up or has caused too many side effects
  • PROMACTA is the only platelet booster that comes in a once-daily tablet and as an oral suspension

To learn more about PROMACTA, go here.

Immune thrombocytopenia, or ITP, is a rare blood condition. People with ITP do not have enough platelets in their blood. A low number of platelets can lead to easy bruising and bleeding.


ITP is considered persistent when lasting 3-12 months after diagnosis and chronic if lasting more than 12 months. Fortunately, persistent or chronic ITP can be managed with treatment, such as PROMACTA.


To learn more about persistent or chronic ITP, go here.

  • PROMACTA is the only platelet booster that comes in a tablet or an oral suspension you can take once a day
  • Platelet boosters work differently: Instead of hurting the immune system, they work with your body to create more platelets so it can make up for the ones it has destroyed. This helps raise platelet counts and improve bruising and bleeding
  • The efficacy of PROMACTA has been studied and proven in adults for up to 7 years

Click here to learn more about how PROMACTA may help. 

PROMACTA is meant to be taken by people who:

  • are 1 year and older, AND
  • have persistent or chronic ITP (lasting >3 months), AND
  • for whom an initial ITP treatment, such as a steroid or intravenous immunoglobulin (IVIg), has failed to keep your platelets up or has caused too many side effects

Curious if PROMACTA is right for you? Learn helpful tips on how to talk about your treatment options with your doctor so you can take a more active role in treatment discussions and decisions.

The side effects of PROMACTA and other platelet boosters are generally mild. The most common side effects of PROMACTA in adults with persistent or chronic ITP are:

  • nausea
  • diarrhea
  • upper respiratory tract infection (symptoms may include runny nose, stuffy nose, and sneezing)
  • vomiting
  • urinary tract infection
  • pain or swelling (inflammation) in your throat or mouth (oropharyngeal pain and pharyngitis)
  • abnormal liver function tests
  • muscle aches

To learn more about side effects, go here

PROMACTA is a prescription medication, so you will have to work with your doctor to see if it is the right treatment for you. 


Click here for tips on how to take a more active role when talking to your doctor about your treatment options.


Questions about cost? Click here to learn about the PROMACTA Co-pay Card and other financial assistance.

Here are 3 important things to know:

  1. PROMACTA can be taken without a meal or it can be taken with a meal low in calcium (50 mg)
  2. PROMACTA should be taken 2 hours before or 4 hours after taking medications like antacids, mineral supplements, or foods that are high in calcium
  3. Weekly doctor’s visits aren’t required for administration of PROMACTA

Click here to get more tips about taking PROMACTA.

First, check out our PROMACTA Patient Support Program by clicking here.


For information on financial support programs for PROMACTA, click here.


Other useful resources include:

A helpful resource for ITP education, advocacy, research, and support, the PDSA website can help you find ITP experts or hematology centers of excellence near you


Helping to ensure that all women with blood disorders are correctly diagnosed and treated at every stage of life


Providing medical, emotional, and lifestyle guidance, as well as helpful daily tips for people and families living with ITP


Furthering the understanding, diagnosis, treatment, and prevention of certain blood and bone disorders through educational resources, tools, and tips


NHLBI promotes the prevention and treatment of heart, lung, and blood diseases


Providing a unified voice for those with rare diseases and their caregivers, seeking to help them so they won’t have to fight their battle alone